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DeCS
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Descriptor English:
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Procollagen-Proline Dioxygenase
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Descriptor Spanish:
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Procolágeno-Prolina Dioxigenasa
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Descriptor Portuguese:
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Procolágeno-Prolina Dioxigenase
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Synonyms English:
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Proline,2-Oxoglutarate 4-Dioxygenase
Protocollagen Prolyl Hydroxylase
Proline Hydroxylase
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Tree Number:
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D08.811.682.690.708.673
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Definition English:
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A mixed-function oxygenase that catalyzes the hydroxylation of a prolyl-glycyl-containing-peptide, usually in PROTOCOLLAGEN, to a hydroxyprolylglycyl-containing-peptide. The enzyme utilizes molecular OXYGEN with a concomitant oxidative decarboxylation of 2-oxoglutarate to SUCCINATE. The enzyme occurs as a tetramer of two alpha and two beta subunits. The beta subunit of procollagen-proline dioxygenase is identical to the enzyme PROTEIN DISULFIDE-ISOMERASES. |
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See Related English:
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Protein Disulfide-Isomerases
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History Note English:
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94; was PROLINE HYDROXYLASE 1972-93 (Prov 1972-73); PROLINE,2-OXOGLUTARATE 4-DIOXYGENASE was PROLINE,2-OXOGLUTARATE DIOXYGENASE see PROLINE HYDROXYLASE 1977-93
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Allowable Qualifiers English:
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Record Number:
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31898
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Unique Identifier:
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D011393
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Occurrence in VHL:
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Similar:
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DeCS CID-10 SciELO LILACS LIS
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